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Vaccinations are being offered to 40 people associated with a day nursery after a child contracted Hepatitis A.
The child who attends the Fun Days Day Nursery in Rhyl, Wales, contracted the virus following a family outbreak of the infection.
There are four confirmed cases of the infection, with the outbreak being investigated by Public Health Wales and the environmental health departments of Conwy and Denbighshire county councils.
Dr Christopher Johnson, consultant in health protection for Public Health Wales, said: "Hepatitis A is a viral infection, usually short lived that has unpleasant symptoms but is rarely serious. Children often only have a very mild illness or do not have symptoms at all.
"Symptoms can include flu-like illness such as tiredness, general aches and pains, headaches and fever, as well as loss of appetite, nausea or vomiting, abdominal pains, jaundice, very dark urine and itchy skin.”
The nursery is co-operating fully with arrangements for vaccination and it is understood the child confirmed with Hepatitis A did not contract the infection while at nursery.
Hepatitis A is contracted when a child eats food or drinks water that is contaminated with the virus or has close contact with a person who is infected with the virus.
Dr Johnson added: "Good handwashing after using the toilet and before preparing or eating food is the best way to prevent the virus spreading.
"Children may pass the virus onto others without having symptoms so we are reminding parents to encourage good hand washing at all times."
Hepatitis A vaccination is not routinely offered on the NHS as the infection is rare in the UK. Those concerned about their health or their child’s health are advised to contact their own GP or NHS Direct Wales.
For more information visit: www.wales.nhs.uk